Key facts about BOTOX®

Did you know BOTOX® is the #1 prescribed branded treatment for Chronic Migraine?* With BOTOX®, you can prevent headaches and migraines before they even start. BOTOX® prevents on average 8 to 9 headache days and migraine/probable migraine days a month (vs 6 to 7 for placebo).

5 things to know

500,000+ Chronic Migraine patients treated with BOTOX® since FDA approval in 2010

1 treatment session in your doctor's office every 12 weeks

Injections take about 15 minutes

Majority of costs covered by most insurance plans. Start saving

Most common side effect is neck pain. Learn more

*Data on File.

†Coverage and out-of-pocket costs vary.

What makes BOTOX® a different type of treatment?

Is BOTOX Right For Me? Is BOTOX Right For Me? Find out all about BOTOX Chronic Migraine, what makes BOTOX a different treatment from other options, and why BOTOX Chronic Migraine could be right for you.

Consider if BOTOX® is right for you

Hear from a BOTOX® Specialist:

“Because Chronic Migraine is a serious condition, it requires a preventive treatment.”

Video transcript

  • BOTOX® is the first FDA-approved preventive Chronic Migraine treatment. Chronic Migraine is different from other headache and migraine conditions—because it's more frequent and severe—so it should be treated differently
  • Unlike acute treatments, BOTOX® prevents headaches and migraines before they even start. Chronic Migraine can take up more than half your month and requires ongoing treatment

What makes Chronic Migraine different from less frequent headaches and migraines, like episodic migraine?

15 or more headache days per month (at least 8 associated with migraine)
14 or fewer headache days per month (some are associated with migraine)
Headaches last longer
Headaches don't last as long
More severe and debilitating
Pain is often less severe

If you have been living with headaches and migraines, taking this short quiz can help you understand if your headaches and migraines could be Chronic Migraine. And, it can help you have a more productive conversation with your doctor.

If you are currently taking migraine treatment, think back to before you started it. If you previously had 15 or more headache or migraine days a month in any 3-month period, you could still have Chronic Migraine.

Take the quiz to find out more

What are the possible side effects of BOTOX®?

What about safety?

Hear from a BOTOX® Specialist:

“In clinical trials, the most common side effect was neck pain, experienced by...9 out of every 100 people taking BOTOX®.”

Video transcript

What it's like to start treatment with BOTOX®

Hear from people like you:

“...any treatment can have its unknowns, but my doctor made me feel really comfortable, and I trust her.”

Video transcript

Key facts about BOTOX®

Hear from a BOTOX® Specialist:

“The BOTOX® injections take about 15 minutes and are done right in the doctor’s office.”

Video transcript

Like with all medications, there's a risk of side effects; the most common for BOTOX® is neck pain, experienced in 9% of people vs 3% for placebo. See below for more information.

Side effects in clinical
studies included:

(in 687 patients)

(in 692 patients)

Partial facial paralysis
Drooping Eyelids
Neck Pain
Musculoskeletal stiffness
Muscular weakness
Muscle pain
Musculoskeletal pain
Muscle spasms
Injection site pain
High blood pressure

These are not all the side effects of BOTOX®. Please see the Important Safety Information below and talk to your doctor about the Summary of Information about BOTOX®.

Wondering about insurance and savings?

Get answers

Talk to the right doctor about Chronic Migraine

What should you expect from BOTOX® treatment?

Find out


BOTOX® may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX®:

  • Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.
  • Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.

There has not been a confirmed serious case of spread of toxin effect away from the injection site when BOTOX® has been used at the recommended dose to treat chronic migraine.

BOTOX® may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of taking BOTOX®. If this happens, do not drive a car, operate machinery, or do other dangerous activities.

Do not receive BOTOX® if you: are allergic to any of its ingredients (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.

The dose of BOTOX® is not the same as, or comparable to, another botulinum toxin product.

Serious and/or immediate allergic reactions have been reported, including itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you experience symptoms; further injection of BOTOX® should be discontinued.

Tell your doctor about all your muscle or nerve conditions such as ALS or Lou Gehrig’s disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX®.

Tell your doctor about all your medical conditions, including if you: have or have had bleeding problems; have plans to have surgery; had surgery on your face; weakness of forehead muscles; trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® can harm your unborn baby); are breastfeeding or plan to (it is not known if BOTOX® passes into breast milk).

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX® with certain medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you received BOTOX® in the past.

Tell your doctor if you received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic injection; take muscle relaxants; take allergy or cold medicines; take sleep medicine; take aspirin-like products or blood thinners.

Other side effects of BOTOX® include: dry mouth, discomfort or pain at injection site, tiredness, headache, neck pain, eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of eyelids, dry eyes; and drooping eyebrows.

For more information refer to the Medication Guide or talk with your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

BOTOX® is a prescription medicine that is injected to prevent headaches in adults with Chronic Migraine who have 15 or more days each month with headache lasting 4 or more hours each day in people 18 years or older.

It is not known whether BOTOX® is safe or effective to prevent headaches in patients with migraine who have 14 or fewer headache days each month (episodic migraine).

Please see BOTOX® full Product Information including Boxed Warning and Medication Guide.

Program Terms, Conditions, and Eligibility Criteria: 1. This offer is good for use only with a valid prescription for BOTOX® (onabotulinumtoxinA). 2. Based on insurance coverage, Chronic Migraine patients can receive up to $700 off per treatment for up to 5 treatments over a 12-month period. Maximum savings limit of $3500 over a 12-month period for people with Chronic Migraine applies; patient out-of-pocket expense may vary. 3. This offer is not valid for use by patients enrolled in Medicare, Medicaid, or other federal or state programs (including any state pharmaceutical assistance programs), or private indemnity or HMO insurance plans that reimburse you for the entire cost of your prescription drugs. Patients may not use this offer if they are Medicare-eligible and enrolled in an employer-sponsored health plan or prescription drug benefit program for retirees. This offer is not valid for cash-paying patients. 4. This offer is valid for 5 treatments over a 12-month period 5. Offer is valid only for BOTOX® and BOTOX® treatment-related costs not covered by insurance. 6. A BOTOX® Savings Program check will be provided upon approval of a claim. The claim must be submitted with treatment details from an Explanation of Benefits (EOB) or a Specialty Pharmacy Provider (SPP) receipt. (If the BOTOX® prescription was filled by a Specialty Pharmacy Provider, both EOB and SPP details must be provided.) All claims must be submitted within 120 days of treatment date. You may be required to provide a copy of your EOB or SPP receipt for your claim to be approved. 7. A BOTOX® Savings Program check may be sent either directly to you or to your selected healthcare provider who provided treatment. For payment to be made directly to your healthcare provider, you must authorize an assignment of benefit during each claim submission. You are not obligated to assign your BOTOX® Savings Program benefit to your healthcare provider to participate in the program. 8. Allergan reserves the right to rescind, revoke, or amend this offer without notice. 9. Offer good only in the USA, including Puerto Rico, at participating retail locations. 10. Void where prohibited by law, taxed, or restricted. 11. This offer is not health insurance. 12. By participating in the BOTOX® Savings Program, you acknowledge that you are an eligible patient and that you understand and agree to comply with the terms and conditions of this offer.

For questions about this program, please call 1-800-44-BOTOX.

Important Safety Information