BOTOX® prevents headaches in adults with Chronic Migraine, 15 or more headache days a month, each lasting 4 or more hours. BOTOX® is not approved for 14 or fewer headache days a month. Prescription only.
Proven for Chronic Migraine for over 15 years*
BOTOX® is the #1 prescribed branded Chronic Migraine preventive treatment.†
*Since FDA approval in 2010.
†Based on IQVIA data from May 2018–June 2025.
Proven for Chronic Migraine for <over 13> years.*
BOTOX® is the #1 prescribed branded injectable preventive Chronic Migraine treatment.†
*FDA approved, 2010.
†2023 Based on IQVIA data from May 2018 to June 2023.
*2023 BOTOX® Chronic Migraine Patient Market Research BOTOX® Current Users (n=78).
†Based on IQVIA data from May 2018 to June 2023
Hear from a Chronic Migraine expert
Chronic Migraine is more common than you may think.
Hear from a Chronic Migraine expert
Chronic Migraine is more common than you may think.
Just 4 treatments a year
(once every 12 weeks),
each taking about
10 minutes†‡§
Administered by a specialist.
Over 1 million patients have treated their Chronic Migraine with BOTOX®‖
BOTOX® injections prevent, on average, 8 to 9 headache days and migraine/probable migraine days a month (vs 6 to 7 for placebo)
Over 1 million patients have treated their Chronic Migraine with BOTOX®‖
In a survey, 99% of current BOTOX® users said they plan to keep using it#
Over 1 million patients have treated their Chronic Migraine with BOTOX®§
*Based on IQVIA data from May 2018–June 2025.
†Starts with 2 treatments 12 weeks apart, then 1 treatment every 12 weeks thereafter (or as recommended by your doctor).
‡BOTOX® injections are given by your doctor.
§Data on file, AbbVie Inc. REF-89020.
‖As of June 2023.
#2023 BOTOX® Chronic Migraine Patient Market Research BOTOX® Current Users (n=78).
Questions about BOTOX®?
We’ve got answers.
You should know that BOTOX® is a prescription preventive treatment for adults with Chronic Migraine. It prevents headaches and migraine attacks* before they even start.†
While you may begin to feel results sooner, it is important to receive 2 treatments 12 weeks apart to get the full benefit of treatment at week 24.
Treatment is done by your doctor every 3 months in their office. Injections are shallow, administered in specific muscles of the head and neck, and take about 10 minutes.‡
The most common side effects in clinical trials were neck pain (9% or 9 out of 100 people taking BOTOX® vs 3% or 3 out of 100 people taking placebo) and headache (5% or 5 out of 100 people taking BOTOX® vs 3% or 3 out of 100 people taking placebo).
*BOTOX® prevents, on average, 8 to 9 headache days and migraine or probable migraine days a month, vs 6 to 7 for placebo.
†Data on File, AbbVie Inc. REF-89746.
‡Data on File, AbbVie Inc. REF-89020.
Please see full Important Safety Information, including Boxed Warning below.
The most common side effects in clinical trials were neck pain (9% or 9 out of 100 people taking BOTOX® vs 3% or 3 out of 100 people taking placebo) and headache (5% or 5 out of 100 people taking BOTOX® vs 3% or 3 out of 100 people taking placebo).
Other side effects occurred less often. If you have questions about side effects or what to expect with BOTOX® treatment, talk with your doctor.
Please see full Important Safety Information, including Boxed Warning below.
